TABLE 2.
GENES WITH > 1.5 FOLD-CHANGE IN EXPRESSION IN PERIPHERAL BLOOD BETWEEN THE ACUTE-STAGE AND RECOVERY-STAGE OF ARDS
| Symbol | Probe Set | Gene Name | Gene ID | Fold Change* |
|---|---|---|---|---|
| PI3 | 203691_at | Peptidase inhibitor 3, skin-derived (SKALP) | 5266 | −2.98 |
| 41469_at | −2.65 | |||
| IL8 | 202859_x_at | Interleukin 8 | 3576 | −2.93 |
| 205592_at | −1.79 | |||
| Unknown | 211781_x_at | Unknown (gb:BC006164.1) | −2.22 | |
| MME | 203435_s_at | Membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) | 4311 | −2.12 |
| PTGS2 | 204748_at | Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5743 | −2.03 |
| SGK | 201739_at | Serum/glucocorticoid regulated kinase | 6446 | −2.03 |
| BNIP3L | 221478_at | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 665 | −1.84 |
| POLB | 203616_at | Polymerase (DNA directed), beta | 5423 | −1.83 |
| STAT1 | 200887_s_at | Signal transducer and activator of transcription 1, 91kDa | 6772 | −1.78 |
| FGL2 | 204834_at | Fibrinogen-like 2 | 10875 | −1.68 |
| GPR177 | 221958_s_at | G protein–coupled receptor 177 | 79971 | −1.58 |
| PIGF | 205077_s_at | Phosphatidylinositol glycan anchor biosynthesis, class F | 5281 | −1.56 |
| CLEC7A | 221698_s_at | C-type lectin domain family 7, member A | 64581 | −1.56 |
| C14orf159 | 218298_s_at | Chromosome 14 open reading frame 159 | 80017 | −1.56 |
| TBCC | 202495_at | Tubulin folding cofactor C | 6903 | −1.56 |
| LY75 | 205668_at | Lymphocyte antigen 75 | 4065 | −1.55 |
| BTRC | 216091_s_at | Beta-transducin repeat containing | 8945 | −1.55 |
| DUSP6 | 208892_s_at | Dual specificity phosphatase 6 | 1848 | −1.52 |
| HIP2 | 202346_at | Huntingtin interacting protein 2 | 3093 | 1.55 |
| OSBPL1A | 208158_s_at | Oxysterol binding protein-like 1A | 114876 | 1.58 |
| STXBP2 | 209367_at | Syntaxin binding protein 2 | 6813 | 1.62 |
| IDI1 | 204615_x_at | Isopentenyl-diphosphate delta isomerase 1 | 3422 | 1.58 |
| 208881_x_at | 1.65 | |||
| HSPA1A / HSPA1B | 200800_s_at | Heat shock 70-kD protein 1A / heat shock 70-kD protein 1B | 3303/3304 | 1.66 |
| GALNT2 | 217788_s_at | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) | 2590 | 1.83 |
| PDGFC | 218718_at | Platelet-derived growth factor C | 56034 | 2.08 |
| HPGD | 203914_x_at | Hydroxyprostaglandin dehydrogenase 15-(NAD) | 3248 | 2.00 |
| 203913_s_at | 2.29 | |||
| GADD45A | 203725_at | Growth arrest and DNA-damage-inducible, alpha | 1647 | 2.38 |
Definition of abbreviation: ARDS, acute respiratory distress syndrome.
*
A negative number of fold change means the gene was down-regulated during the acute stage of ARDS, and a positive number of fold change means the gene was up-regulated during the acute stage.