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. 2008 May 16;8:e27.

Table 9.

Treatment of carbon monoxide and cyanide toxicity

Carbon monoxide – awake Carbon monoxide – obtunded Cyanide
High flow by mask oxygen (FiO2 100%) until carboxyhemoglobin < 10% Intubate Cardiovascular support
  100% oxygen via positive pressure ventilation Sodium nitrite only if not responding and high likelihood of diagnosis HCN toxicity
  Hyperbaria used if patient not responding to 100% (specific indications remain unclear) Sodium thiosulfate