Table 9.
Treatment of carbon monoxide and cyanide toxicity
Carbon monoxide – awake | Carbon monoxide – obtunded | Cyanide |
High flow by mask oxygen (FiO2 100%) until carboxyhemoglobin < 10% | Intubate | Cardiovascular support |
100% oxygen via positive pressure ventilation | Sodium nitrite only if not responding and high likelihood of diagnosis HCN toxicity | |
Hyperbaria used if patient not responding to 100% (specific indications remain unclear) | Sodium thiosulfate |