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. 2007 Jun 30;5(2):145–151. doi: 10.1093/ecam/nem051

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© 2007 The Author(s).

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — The effect of antidromic stimulation of the unilateral dorsal roots (DR) of lumbar segments on ipsilateral MBF. (A) Schematic diagram of CGRP-related antidromic vasodilative action in muscles. (B) Sample recordings of blood flow of the biceps femoris muscle response to antidromic electrical stimulation of the L4 DR. Parameters of electrical stimulation are indicated. (C) The means and SEM of MBF responses to stimulation of L4-L5 DR before (closed circles) and after (open circles) topical application of hCGRP (8–37) (10⁻⁴ M). Changes in MBF were calculated every 30 s and are expressed as percentages of the pre-stimulus values just before stimulation (ordinate). The horizontal bar between the dashed vertical lines indicates the time during DR stimulation. Onset of electrical stimulation of DR is expressed as zero (abscissa). *P < 0.05; **P < 0.01; significantly different from pre-stimulus control values. Modified from Sato et al. (27).