Table 1.
Reference: | Age/Sex | Karyotype | HMGA2 Rearrangement by FISH | HMGA2 Immunoperoxidase | |
---|---|---|---|---|---|
1 | Horsman 1991 [11] | 42/F | 45-50,XX,-12,-5,+der(5)t(5q15;?),-16,+der(16)t(5q;16q),-15,+der(15)t(15ql3;?)(l-4),+/-frag | NP | NP |
2 | Betz 1995 [14] | 32/F | 46,XX,t(7;12)(q22-31;q13-14)[14] | NP | NP |
3 | Kazmierczak 1995 [12] & 1998 [13] | 44/F | 46,XX/46,XX,t(5;12)(q31;p11.2),der(12)inv(12)(p11.2;q14)t(5;12)(q31;p11.2)[50] | Positive | NP |
4 | Kenny-Moynihan 1996 [15] | 16/F | 45,X,-X[8] | NP | NP |
5 | Nucci 1999 &Nucci 2001 [16, 17] | 18*/F | 46,XX,t(8;12)(p12;q15) | Negative | Positive |
6 | Micci 2006 [18] | 44/F | 46,XX,t(11;12)(q23;q15)[16] | Negative | Positive |
7 | Rabban 2006 [38] | 34/F | NP | Positive | Negative |
8 | Medeira 2007 [19] | 53/F | 46, XX,t(1;12)(p32;q15)[20] | Positive | NP |
9 | 49/F | 46, XX | Negative | NP | |
10 | Current Case | 72/F | 46,XX,t(12;21)(q15;q21.1)[20] | Positive | Positive |
NP = not performed;
Patient initially presented at age 18, but study material for cytogenetics was obtained on resection of a second recurrence at age 24