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. Author manuscript; available in PMC: 2008 May 27.
Published in final edited form as: Neuroscience. 2008 Jan 12;152(2):360–370. doi: 10.1016/j.neuroscience.2008.01.004

Figure 4.

Figure 4

Post-embedding electron microscopic distribution of pLIMK-IR within axospinous synapses in striatum radiatum of the hippocampus CA1 region. In young OVX + E female rat (A) and in young OVX + Veh female rat (B), pLIMK immunogold particles (10 nm in diameter) are seen in pre-synaptic (Bins 6, 7 and 8), cleft (Bin 5) and post-synaptic (Bins 1, 2, and 4) compartments of the synapse. pLIMK immunogold particles are affiliated with the postsynaptic density (psd) and in the post-synaptic pool (Bins 1, 2, and 4) as well as pre-synaptically (Bins 6, 7 and 8) in an aged OVX + E female rat (C). t, terminal; sp, spine; OVX, ovariectomized; E, 17-B estradiol treated; Veh, vehicle treated. Scale bars for A–C: 0.1 5m.