Figure 6.

Relative mRNA expression of nuclear receptors along the longitudinal axis of the small intestine under basal conditions. For the proximal, middle and distal part of the small intestine, gene expression levels of Ppars, Lxrs and Fxr were determined after 2 weeks of low-fat diet intervention. qPCR data of the nuclear receptors are visualized as the mean expression of individual mice ± SE. Expression in the middle and distal part of the small intestine is relative to the expression in the proximal part, which was set to 1. a, b, and c indicate significant (p < 0.05, two-tailed Student's t test) differential gene expression between the distinct parts of the small intestine (a between the proximal and middle part, b between the middle and distal part and c between the proximal and distal part).