Table 3.
Spearman Rank correlations between investigated variables and proteinuria and endothelial function (FMD) in all proteinuric patients and in the separate groups
| All Proteinuric Patients (n = 121)
|
Nonnephrotic Proteinuria (<3.5 g/d) (n = 43)
|
Nephrotic-Range Proteinuria without Amyloidosis (>3.5 g/d) (n = 39)
|
Nephrotic-Range Proteinuria with Amyloidosis (>3.5 g/d) (n = 39)
|
|||||
|---|---|---|---|---|---|---|---|---|
| Proteinuria (mg/d) | FMD (%) | Proteinuria (mg/d) | FMD (%) | Proteinuria (mg/d) | FMD (%) | Proteinuria (mg/d) | FMD (%) | |
| Age, yr | NS | NS | NS | NS | NS | NS | NS | NS |
| GFR, ml/min per 1.73 m2 | 0.27a | NS | NS | NS | NS | NS | NS | NS |
| Serum albumin, g/dl | −0.60b | 0.48b | −0.34a | NS | NS | NS | NS | NS |
| BMI, kg/m2 | NS | NS | NS | NS | NS | NS | NS | NS |
| hsCRP, mg/L | 0.47b | −0.40b | 0.53b | NS | −0.26a | −0.43b | 0.68b | −0.54b |
| HOMA | 0.32b | −0.31a | NS | NS | NS | NS | 0.37a | NS |
| Triglycerides, mg/dl | 0.64b | −0.38b | NS | NS | NS | NS | NS | NS |
| Total Cholesterol, mg/dl | 0.57a | −0.25a | NS | NS | 0.33a | NS | NS | NS |
| LDL Cholesterol, mg/dl | 0.60b | −0.38b | NS | NS | NS | NS | NS | NS |
| Proteinuria, mg/d | NA | −0.55b | NA | NS | NA | NS | NA | −0.51b |
| FMD, % | −0.55b | NA | NS | NA | NS | NA | −0.51b | NA |
| L-Arginine, μmol/L | −0.27a | NS | NS | NS | NS | NS | NS | NS |
| L-Arginine/ADMA | −0.88b | 0.59b | −0.68b | NS | −0.91b | NS | −0.47b | 0.41b |
| SDMA, μmol/L | 0.85b | −0.58b | 0.72b | NS | 0.77b | NS | 0.39a | −0.39a |
| ADMA, μmol/L | 0.88b | −0.60b | 0.83b | NS | 0.93b | NS | 0.43b | −0.42b |
NA, not applicable; NS, not significant.
P < 0.05;
P < 0.001.