Table 1.

Summary of the characteristics of the five methods^a

Method	Species	Total Features on the Platform	Glomerulus-Enriched Genes Reported	Selection Criteria
EST libraries comparison	Mouse	13,368 EST	497	P < 0.05, more than three-fold difference with whole kidney tissue
GlomChip profiling	Mouse	18,496 probes	357	P < 0.05, more than two-fold difference with nonglomerular kidney tissue
Affymetrix profiling	Mouse	45,101 probes	1013	P < 0.05, more than two-fold difference with nonglomerular kidney tissue
SAGE profiling	Human	∼50,000 tags	153	P < 0.01, seven-fold or more difference with at least three nephron libraries
Stanford cDNA microarray profiling	Human	41,859 probes	102	Cluster analysis, genes predominantly expressed in glomeruli than others

^aSpecies column shows the RNA sample source for the methods. For each method, total features on the platforms, number of genes identified (mouse/human), and the selection criteria for glomerulus-enriched genes are listed.