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. 2008 Feb;19(2):329–338. doi: 10.1681/ASN.2007040510

Figure 3.

Figure 3.

Dosage effect of PAI-1R on glucose levels (A), albuminuria (B), and glomerular histology (C) in diabetic db/db mice. *P < 0.05 versus uninephrectomized nondiabetic control db/m mice at 22 wk of age (NC; n = 9); #P < 0.05 versus uninephrectomized diabetic db/db mice at 20 wk of age (DC20; n = 5); §P < 0.05 versus uninephrectomized diabetic db/db mice at 22 wk of age, treated with PBS for 2 wk (DC22; n = 5). PAI-1R25, 22-wk diabetic mice treated with PAI-1R at 25 μg/mouse from weeks 20 to 22 (n = 7); PAI-1R100, 22-wk diabetic mice treated with PAI-1R at 100 μg/mouse from weeks 20 to 22 (n = 7).