Table 1.
Fold change of protease inhibitor and activator genes significantly increased in TSLP Tg and TSLPTg FcIIb−/− mice (more than two-fold change, P < 0.05)a
| Parameter | Gene Symbol | TSLP/WT
|
TSLP FcIIb−/−/TSLP, Males | |
|---|---|---|---|---|
| Females | Males | |||
| tPA | Plat | NS | NS | 30.64 |
| Serine protease inhibitor, clade E, PN-1 | SerpinE2 | 2.89 | NS | 23.07 |
| Cathepsin S | Ctss | 2.82 | NS | 6.01 |
| PAR-1 | F2r | NS | NS | 5.30 |
| Coagulation factor II (thrombin) receptor | F2r | NS | NS | 5.30 |
| Kallikrein 8 | Klk8 | NS | 4.44 | 3.53 |
a
PAR-1, proteinase activated receptor-1.