Table 1.
Baseline characteristicsa
| Characteristic | Sevelamer (n = 33) | Calcium (n = 35) | P |
|---|---|---|---|
| Gender (M/F; n [%]) | 22/11 (67/33) | 18/17 (51/49) | 0.23 |
| Race | >0.99 | ||
| white | 32 (97) | 34 (97) | |
| black | 1 (3) | 1 (3) | |
| Age (yr; mean ± SD) | 55.5 ± 15.4 | 53.9 ± 13.7 | 0.53 |
| Menopausal status (n [%]) | 0.0097 | ||
| premenopausal | 0 (0) | 8 (47) | |
| postmenopausal | 11 (100) | 9 (53) | |
| BMI (kg/m2; mean ± SD) | 23.5 ± 3.5 | 25.3 ± 3.8 | 0.09 |
| Smoker (n [%]) | 8 (24) | 3 (9) | 0.10 |
| Diabetes (n [%]) | 2 (6) | 8 (23) | 0.08 |
| Hypertension (n [%]) | 24 (73) | 25 (71) | >0.99 |
| Primary cause of stage 5 CKD (n [%]) | 0.18 | ||
| hypertension | 2 (6.1) | 6 (17.1) | |
| glomerulonephritis | 8 (24.2) | 7 (20.0) | |
| diabetes | 2 (6.1) | 7 (20.0) | |
| pyelonephritis | 3 (9.1) | 3 (8.6) | |
| polycystic kidneys | 3 (9.1) | 2 (5.7) | |
| interstitial nephrosis | 4 (12.1) | 0 (0) | |
| other | 11 (33.3) | 10 (28.6) | |
| Dialysis vintage (mo; median [range]) | 23 (4 to 222) | 25 (2 to 181) | 0.49 |
| Phosphate binder use (in 30 d before screening; n [%]) | 33 (100) | 35 (100) | 0.07 |
| calcium carbonate | 31 (94) | 32 (91) | |
| sevelamer | 1 (3) | 1 (3) | |
| calcium carbonate + sevelamer | 1 (3) | 0 (0) | |
| calcium carbonate + aluminum | 0 (0) | 2 (6) | |
| Vitamin D use (in 12 mo before screening; n [%]) | 22 (67) | 24 (69) | 1.0 |
a
BMI, body mass index.