Table 1.
Summary of nucleotide and amino acid sequencea differences between the GenBank-deposited sequences of BR/90, the BR/90 amplicons used to generate our infectious cDNAs and various cloned cDNAs.
| Base position (codon)b | Coding region | BR/90 GenBankc | BR/90 amplicons | pACDV1rep NS1*NS3* | pACDV1 T7-C-NS1 | pBACDV1flc NS1*NS3* | pBACDV1flc |
|---|---|---|---|---|---|---|---|
| 325 | C | A | G | G | G | G | |
| 1213 | E | A | U | U | U | U | |
| 1258 | E | U | C | C | C | C | |
| 1291 | E | U | C | C | C | C | |
| 1378 | E | A | G | G | G | G | |
| 1639 | E | C | U | U | U | U | |
| 1648 | E | U | C | C | C | C | |
| 2719 | NS1 | G | A | A | A | A | |
| 3159 (247) | NS1 | A (Y)d | A (Y)d | G (C) | G (C) | A (Y)d | |
|
| |||||||
| 3265 | NS1 | C | U | U | U | U | |
| 3346 | NS1 | U | U | C | C | U | |
| 3424 | NS1 | C | U | U | U | U | |
| 3907 (144) | NS2A | C (H) | G (Q)d | G (Q)d | G (Q)d | G (Q)d | |
|
| |||||||
| 4627 | NS3 | G | A | A | A | A | |
| 5250 (211) | NS3 | A (Q)d | A (Q)d | G (R) | G (R) | A (Q)d | |
|
| |||||||
| 5413 | NS3 | A | A | A | A | G | |
| 6148 | NS3 | U | U | C | C | C | |
| 6598 | NS4A | A | A | G | G | G | |
| 10195 | NS5 | G | G | A | A | A | |
| 10258 | NS5 | A | A | G | G | G | |
a
Encoded amino acid sequences, when different, are shown in “()”.
b
Position of nucleotide change (within genome) and codon change (within the individual protein-encoding region).
c