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Tumor Incidence in Albumin-tv-a mice
| TSG Genotype | RCAS Virus | Age (Months) | Tumor Incidence | Metastasis Incidence |
|---|---|---|---|---|
| Trp53 null | PyMT | 6 | 10/18 | 3/10 |
| Trp53 null | PyMT | 8 | 3/6 | 0/3 |
| Trp53 null | GFP | 12 | 1/10 | 0/1 |
| Trp53 null | GFP | 15 | 1/15 | 0/1 |
| Ink4a/Arf null* | PyMT | 6 | 5/15 | 1/5 |
| Trp53, Ink4a/Arf null | PyMT | 4 | 8/9 | 2/8 |
| Trp53, Ink4a/Arf null | PyMT | 6 | 8/9 | 5/8 |
| Trp53, Ink4a/Arf null | GFP | 9 | 0/17 | N/A |
TSG = tumor suppressor gene
germline deletion
