Table 2. Proliferative T-cell Responses to HPV-16 Synthetic Peptides by Group and HPV-status.
Patients (N = 74) | Healthy Controls (N = 28) | |||||
---|---|---|---|---|---|---|
Peptide | All | HPV16+ | HPV16- | All | HPV16+ | HPV16- |
E624-45 | 41% (30/74) | 14% (2/14)§ | 47% (28/60)§ | 46% (13/28) | 67% (2/3) | 44% (11/25) |
E744-57 | 42% (31/74) | 14% (2/14)§ | 48% (29/60)§ | 46% (13/28) | 67% (2/3) | 44% (11/25) |
L1382-396 | 37% (27/74)* | 7% (1/14)§ | 43% (26/60)§ | 61% (17/28)* | 67% (2/3) | 60% (15/25) |
Note: The percentages reflect the number of subjects with SI≥ 3.0 (i.e. responders)/number of subjects tested.
indicates a significant difference between patients and control in proliferative response, p < 0.05.
indicates a significant difference between HPV16+ and HPV16- patients in proliferative response, p < 0.05.