Table I. Quantitative ultrastructural analysis of synapses with or without Pclo28.
Parameter | Control | +Pclo28 |
---|---|---|
AZ length (nm) | 0.258 ± 0.142 | 0.229 ± 0.102 |
Docked SVs/AV length (n/μm) | 13.87 ± 6.26 | 14.29 ± 5.30 |
SV density (n/μm2) | 163.8 ± 58.36 | 169.0 ± 49.02 |
Percentage of SVs labeled | 20.4 ± 12.5% | 24.5 ± 14.8% |
All data are from boutons with at least two clearly labeled synaptic vesicles opposed to a distinct synaptic junction. All parameters were measured by an observer blind to phenotype. n = 64 boutons with 66 active zones for control and 53 boutons with 55 active zones for +Pclo28. Data are shown ± standard deviation. t tests revealed no significant differences, with no P < 0.05.