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Six stages of phagocytosis are shown: i, particle engagement; i, phagocytic cup formation; iii, nascent phagosome (1–2 min after sealing); iv, early phagosome (2–10 min after sealing); v, late phagosome (10–30 min after sealing); vi, phagolysosome (>30 min after sealing). As the phagosome matures, it undergoes multiple sequential interactions with early endosomes (EE), late endosomes (LE), and lysosomes (Ly).
