Figure 8.

Expression of contractile VSMC markers in hVSMC. (A through C) Calponin (A), α-smooth muscle actin (α-SMA) (B), heavy-chain myosin (MHSCM) (C), and SM22 α (D) message levels detected by RT-PCR were low in hVSMC in basal conditions (□, group A) and in the presence of high-phosphorus media (▪, group B). BMP-7 (□, group C) induced expression of each of the marker proteins. Data were normalized to the expression level in basal culture conditions and expressed as fold induction (mean ± SEM, n = 3).