Table 2.

Effects of lisinopril treatment on proteinuria, tubular damage, and C3 and IgG accumulation in proximal tubules and interstitial F4/80⁺ cells in WT mice receiving BSA^a

Group	Proteinuria (mg/d)	Tubular Damage (Score)	Tubular Staining (Score)		F4/80+ Cells (n/HPF)
			C3	IgG
WT + BSA (n = 4)	36 ± 6	1.10 ± 0.20	1.3 ± 0.1	2.1 ± 0.2	49 ± 3
WT + BSA + lisinopril (n = 6)	12 ± 4b	0.22 ± 0.10c	0.5 ± 0.1c	0.9 ± 0.2c	20 ± 5c

^aData are means ± SEM. Tubular C3 staining refers to abnormal intratubular C3 accumulation (see the Concise Methods section).

^bP < 0.05,

^cP < 0.01 versus WT + BSA.