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Modulatory effects of PACAP vs. anti-PACAP reagents on the phase-shifting effect of Glu on the neuronal activity rhythm. (A) The differential modulatory effects of PACAP and P6–38 in early vs. late night. (B) Summary of various anti-PACAP reagents on the Glu-induced phase delay at CT 14. n = 3 for all conditions, except for P6–38 + Glu and P6–27 + Glu, where n = 4 and 6, respectively. ∗, P < 0.05; ∗∗, P < 0.01.
