Table 1.
Loss of function of scpl-1 results in a defect in egg laying
| Strain | RNAi | Line | Serotonin |
Imipramine |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| + | (+) | (−) | − | + | (+) | (−) | − | |||
| N2 | scpl-1a full | a | 5 | 3 | 2 | 0 | 8 | 2 | 0 | 0 |
| b | 7 | 1 | 0 | 1 | 9 | 0 | 1 | 0 | ||
| N2 | scpl-1b full | a | 7 | 1 | 1 | 0 | 9 | 1 | 0 | 0 |
| b | 8 | 1 | 1 | 0 | 10 | 0 | 0 | 0 | ||
| N2 | empty vector | a | 10 | 0 | 0 | 0 | 10 | 0 | 0 | 0 |
| b | 9 | 1 | 0 | 0 | 8 | 2 | 0 | 0 | ||
| unc-89 (tm752) | scpl-1b full | a | 7 | 2 | 1 | 0 | 10 | 0 | 0 | 0 |
| b | 9 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | ||
| unc-89 (tm752) | empty vector | a | 9 | 1 | 0 | 0 | 9 | 1 | 0 | 0 |
| b | 10 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | ||
| unc-89 (su75) | scpl-1b full | a | 8 | 1 | 0 | 1 | 9 | 1 | 0 | 0 |
| b | 7 | 2 | 1 | 0 | 10 | 0 | 0 | 0 | ||
| unc-89 (su75) | empty vector | a | 8 | 2 | 0 | 0 | 10 | 0 | 0 | 0 |
| b | 9 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | ||
+, more than 8 eggs; (+), 4–7 eggs; (−), 1–3 eggs; and −, 0 eggs.