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. 2008 Jun;19(6):2650–2660. doi: 10.1091/mbc.E07-10-1067

Figure 2.

Figure 2.

Effects of knockdown of BIG2 and/or BIG1, or AP-1 on the localization of endosomal Rab proteins. HeLa cells transiently transfected with EGFP-Rab11 (a–e), EYFP-Rab4 (f–j) or EGFP-Rab5 (k–o) were mock-treated (a, f, and k) or treated with a pool of siRNAs for BIG1 (b, g and l), BIG2 (c, h and m), BIG1+BIG2 (d, i, and n), or the AP-1 μ1A subunit (e, j, and o), as described in Materials and Methods.