Effect of the E2FP peptide on (A) membrane rupture, i.e., leakage, (B) membrane phospholipid mixing of the outer monolayer, i.e., hemifusion, and (C) membrane phospholipid mixing of the inner monolayer, i.e., fusion, of fluorescent probes encapsulated in LUVs containing different lipid compositions at different lipid/peptide molar ratios. The lipid compositions used were EPC/Chol at a molar ratio of 5:1 (○), BPS/Chol at a molar ratio of 5:1 (⋄), EPG/Chol at a molar ratio of 5:1 (□), EPA/Chol at a molar ratio of 5:1 (▵), liver extract lipids (∇), EPC/SM/Chol at a molar ratio of 5:1:1 (◃), EPC/SM/Chol at a molar ratio of 52.18.30 (◃), EPC (•), EPC/LPC at a molar ratio of 5:1 (▪), and EPC/TPE at a molar ratio of 5:1 (▾).