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. 2008 Mar 27;10(2):R27. doi: 10.1186/bcr1984

Table 2.

Types of PIK3CA mutations that were detected

Patient Treatment category Exon 9 Exon 20
1 FAC/FEC E545K
2 FAC/FEC H1047R
3 FAC/FEC H1047R
4 FAC/FEC E542K
5 FAC/FEC E545K
6 FAC/FEC H1047R
7 FAC/FEC E545K
8 FAC/FEC E545K
9 FAC/FEC H1047R
10 FAC/FEC E545K
11 FAC/FEC E545K
12 FAC/FEC E545K
13 TFAC/TFEC Q546R
14 TFAC/TFEC H1047T
15 TFAC/TFEC H1047R
16 TFAC/TFEC H1047R
17 TFAC/TFEC H1047R
18 TFAC/TFEC E545K
19 TFAC/TFEC E542K
20 TFAC/TFEC E542V
21 TFAC/TFEC G1049R
22 TFAC/TFEC H1047R
23 TFAC/TFEC H1047R

Exon 1 mutations were also examined but no mutations were found. FAC, 5-fluoruracil, doxorubicin, and cyclophosphamide; FEC, 5-fluoruracil, epirubicin, and cyclophosphamide; PIK3CA, phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; TFAC, paclitaxel followed by 5-fluoruracil, doxorubicin, and cyclophosphamide; TFEC, paclitaxel followed by 5-fluoruracil, epirubicin, and cyclophosphamide.