Table 5.

Multivariate logistic regression analysis of established and experimental factors for predicting a pathological complete response, irrespective of study treatment: clinical response after two cycles excluded from second analysis

	First analysis			Second analysis
	Odds ratio	95% CI	p Value	Odds ratio	95% CI	p Value
Menopausal status	1.63	0.44 to 6.05	0.467	1.89	0.55 to 6.51	0.312
Tumour size	1.75	0.46 to 6.68	0.411	1.80	0.51 to 6.40	0.363
Clinical nodal status	5.48	1.24 to 24.16	0.025	5.44	1.35 to 21.87	0.017
Grade	0.21	0.03 to 1.33	0.098	0.16	0.03 to 0.91	0.039
Clinical response after two cycles	3.68	0.90 to 15.03	0.069	-	-	-
Hormonal receptor	27.00	2.21 to 330.57	0.010	7.83	1.24 to 49.42	0.029
Ki-67	0.75	0.16 to 3.56	0.716	0.78	0.18 to 3.39	0.740
HER2	4.09	0.70 to 24.08	0.119	3.66	0.69 to 19.30	0.126
p53	4.11	0.73 to 23.01	0.108	2.55	0.56 to 11.66	0.227
bcl-2	3.75	0.35 to 39.54	0.272	4.98	0.53 to 46.95	0.161

HER2, human epidermal growth factor receptor 2.