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. 2008 Apr 22;10(2):R33. doi: 10.1186/bcr1996

Table 2.

Antiproliferative effect of NVP-AUY922 against primary breast cancer

Cell line IC50 IC70

nM
MAXF 1162 304 505
MAXF 1322 29 48
MAXF 1384 209 477
MAXF 401 78 295
MAXF 574 >10,000 >10,000
MAXF 583 333 569

The concentrations of NVP-AUY922 that inhibit colony formation by 50% (IC50) or 70% (IC70) were determined (Oncotest GmbH, Freiburg, Germany) [24].