Table 2.
Antiproliferative effect of NVP-AUY922 against primary breast cancer
| Cell line | IC50 | IC70 |
| nM | ||
| MAXF 1162 | 304 | 505 |
| MAXF 1322 | 29 | 48 |
| MAXF 1384 | 209 | 477 |
| MAXF 401 | 78 | 295 |
| MAXF 574 | >10,000 | >10,000 |
| MAXF 583 | 333 | 569 |
The concentrations of NVP-AUY922 that inhibit colony formation by 50% (IC50) or 70% (IC70) were determined (Oncotest GmbH, Freiburg, Germany) [24].