Abstract
Two children developed bacterial meningitis within five days of measles-mumps-rubella (MMR) immunisation. Diagnosis was delayed because symptoms were attributed to the vaccine, although both had a raised C-reactive protein. Fever or rash within five days of MMR vaccination are unlikely to be due to the vaccine and a raised C-reactive protein suggests bacterial infection.
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Selected References
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- Black S. B., Cherry J. D., Shinefield H. R., Fireman B., Christenson P., Lampert D. Apparent decreased risk of invasive bacterial disease after heterologous childhood immunization. Am J Dis Child. 1991 Jul;145(7):746–749. [PubMed] [Google Scholar]
- Landrigan P. J., Witte J. J. Neurologic disorders following live measles-virus vaccination. JAMA. 1973 Mar 26;223(13):1459–1462. [PubMed] [Google Scholar]
- Marzouk O., Bestwick K., Thomson A. P., Sills J. A., Hart C. A. Variation in serum C-reactive protein across the clinical spectrum of meningococcal disease. Acta Paediatr. 1993 Sep;82(9):729–733. doi: 10.1111/j.1651-2227.1993.tb12547.x. [DOI] [PubMed] [Google Scholar]
- Marzouk O., Thomson A. P., Sills J. A., Hart C. A., Harris F. Features and outcome in meningococcal disease presenting with maculopapular rash. Arch Dis Child. 1991 Apr;66(4):485–487. doi: 10.1136/adc.66.4.485. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Miller E., Goldacre M., Pugh S., Colville A., Farrington P., Flower A., Nash J., MacFarlane L., Tettmar R. Risk of aseptic meningitis after measles, mumps, and rubella vaccine in UK children. Lancet. 1993 Apr 17;341(8851):979–982. doi: 10.1016/0140-6736(93)91069-x. [DOI] [PubMed] [Google Scholar]
- Peltola H., Heinonen O. P. Frequency of true adverse reactions to measles-mumps-rubella vaccine. A double-blind placebo-controlled trial in twins. Lancet. 1986 Apr 26;1(8487):939–942. doi: 10.1016/s0140-6736(86)91044-5. [DOI] [PubMed] [Google Scholar]