Table 2.
Baseline function
| Group | Genotype (tTA/PKCβ*) | No. | LVSP, mmHg | LVEDP, mmHg | HR, bpm | RPP, 103 mmHg/min |
|---|---|---|---|---|---|---|
| β-Tx, unpaced | +/+ | 8f | 131 ± 8 | 7 ± 1 | 331 ± 17 | 41 ± 5† |
| Control, unpaced | −/+ | 3f | 84 ± 11 | 6 ± 1 | 314 ± 27 | 25 ± 5 |
| +/− | 2m, 2f | 123 ± 20 | 6 ± 0 | 286 ± 49 | 31 ± 3 | |
| −/− | 4m | 90 ± 4 | 7 ± 1 | 332 ± 29 | 27 ± 2 | |
| Pooled | 6m, 5f | 104 ± 12 | 6 ± 1 | 310 ± 24 | 29 ± 2 | |
| β-Tx, paced | +/+ | 5m, 3f | 106 ± 6 | 8 ± 1 | 420 ± 0 | 45 ± 3† |
| Control, paced | −/+ | 1m, 6f | 84 ± 4 | 8 ± 1 | 420 ± 0 | 35 ± 2 |
Data are shown as means ± SEM. LVSP, left ventricular systolic pressure; LVEDP, LV end-diastolic pressure; HR, heart rate; bpm, beats per min; RPP, rate pressure product; m, male; f, female. †, P < 0.05 vs. controls.