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. 2003 Oct 6;3:10. doi: 10.1186/1471-2415-3-10

Figure 1.

Figure 1

Immunolocalization of MMP-1 in intact corneal epithelium at 48 hours is shown for each treatment group. Panel a: artificial tears; panel b: Ciprofloxacin 0.3%; panel c: Ofloxacin 0.3%; panel d: Levofloxacin 0.5%. A photomicrograph of the artificial tear group shows negative corneal staining for MMP-1. However, intense corneal epithelial and superficial stromal expression of MMP-1 was identified in intact corneal epithelium groups treated with fluoroquinolone eye drops (panel's b-d). The presence of MMP-1 was detected mostly in the corneal epithelial cells (arrows). (Immunohistochemistry, ×400 magnification).