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Phenotypes resulting from genetic ablation or mutations of the orphan nuclear receptor SF-1.
| Organism | Mouse | Human | |
| Genotype | SF-1 -/- | SF-1 +/- | SF-1 m/+ ou SF-1 m/m |
| Adrenal | - Agenesis | - Histological defects - Hyporesponse to stress - Compensatory growth defects |
- Insufficiency (agenesis or dysgenesis) |
| Testis | - Agenesis - Sex reversal |
- Sex reversal | |
| Ovary | - Agenesis | - Normal | |
| VMH | - Agenesis - Obesity caused by absence of the VMH (8 weeks) |
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| Pituitary | - Defects of gonadotrope cells | ||
