Figure 1.

The cyclin D1 promoter is activated by SV40 small t. (A) The −1745CD1LUC reporter was transfected with either the control plasmid pw2t dl888 or the small t expression vector. For the dose response, a representative example from three separate experiments is shown for increasing amounts of transfected expression plasmid normalized to the effect of vector alone. For the effect of pw2t (n = 17 separate transfections) or the CMV small t expression plasmid (n = 7), the data are expressed as mean ± SEM. (B) The −1745CD1LUC reporter was transfected with the SV40 small t expression vector in the cell lines indicated. The data are shown expressed as mean ± SEM with the number of experiments shown as N.