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. 2008 Apr 27;336(7655):1223–1227. doi: 10.1136/bmj.39545.852616.BE

Table 3.

 Number of 25 mg capsules of nortriptyline or placebo used by trial arm by time

Variable Median (interquartile range)* z score, P value†
Quit day:
 Nortriptyline 2 (2-3) −0.22, 0.83
 Placebo 2 (2-3)
Week 1:
 Nortriptyline 3 (2-3) −1.05, 0.29
 Placebo 3 (3-3)
Week 2:
 Nortriptyline 3 (2-3) −3.08, 0.002
 Placebo 3 (3-3)
Week 3:
 Nortriptyline 3 (2-3) −2.78, 0.006
 Placebo 3 (3-3)
Week 4:
 Nortriptyline 3 (1-3) −2.66, 0.008
 Placebo 3 (2-3)

*Among those using trial drug at this point.

†Difference between trial arms (Mann-Whitney U test).