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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Biol Psychiatry. 2008 Feb 20;63(11):1007–1012. doi: 10.1016/j.biopsych.2007.10.018

Figure 2.

Figure 2

NE replacement alters anxiety behavior in Dbh −/− mice. DOPS + benserazide or vehicle was administered approximately five hours prior to EPM testing, when brain restoration of NE peaks in Dbh −/− mice treated with DOPS. Shown is percent open arm time of Dbh −/− mice given vehicle or cocaine (10 mg/kg, i.p.) 20 minutes before the five minute EPM test. *p<0.05 compared to Vehicle-Cocaine group (N=6–8 per group).