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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Biol Psychiatry. 2008 Feb 20;63(11):1007–1012. doi: 10.1016/j.biopsych.2007.10.018

Figure 3.

Figure 3

Disulfiram attenuates cocaine-induced anxiety in Dbh +/− mice. Dbh +/− mice were injected with disulfiram (3 × 200 mg/kg, i.p., two hours between each injection) or vehicle. Two hours following the last disulfiram treatment, mice were injected with saline or cocaine (10 mg/kg, i.p.), and tested in the EPM 20 minutes later. Shown is percent open arm time during the five minute EPM test. *p < 0.05 compared to Vehicle-Saline group (N=8 per group).