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. Author manuscript; available in PMC: 2008 May 30.
Published in final edited form as: Free Radic Biol Med. 2006 Jul 15;41(8):1315–1324. doi: 10.1016/j.freeradbiomed.2006.07.014

Fig. 3.

Fig. 3

N-acetylcysteine augments endostatin's ability to suppress invasion of HNSCC cells. The ability of NAC and endostatin to inhibit the ability of calcein-loaded HNSCC cells to invade a synthetic basement membrane was evaluated using a commercially available cell invasion assay kit. Notably, in each cell line (n = 5) and in every experiment conducted (n = 8), the combination of NAC pretreatment with inclusion of NAC and endostatin during invasion inhibited HNSCC invasive capacities (p ≤ 0.05, Yates corrected χ2 test).