Table 1.

Effects of GSH, NAC, GSSG, and endostatin on MMP-9 functional activity

Experimental group	Equimolar	100×	250×	500×
GSH	−7.1 ± 10.3	−47.3 ± 5.6 *	−52.8 ± 6.8 *	−60.6 ± 4.7 *
NAC	−22.0 ± 9.8	−47.3 ± 4.3 *	−61.5 ± 11.6 *	−57.2 ± 6.3 *
GSSG	−8.3 ± 9.4	−12.9 ± 10.6	−13.0 ± 11.0	−1.1 ± 13.2
Single-dose experiments
Endostatin (10 μg/ml)	+4.2 ± 14.4
Endostatin (10 μg/ml) + 250 × NAC	−43.5 ± 9.0
EDTA (10 mM)	−95.4 ± 0.02

N = 5 for each experimental group, mean percentage change in MMP-9 activity ± SEM.

^*p < 0.05, Yates corrected χ² test.