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. 2008 Jun 11;3(6):e2398. doi: 10.1371/journal.pone.0002398

Figure 11. Significant gene pathway changes in the hippocampi of male and female rats maintained on the IF diet.

Figure 11

Significantly altered genes in the male and female hippocampi from the different dietary regimes were clustered into functional gene pathways. In the hippocampi from male rats on the IF diet, there were 43 significantly altered gene pathways, of which 26 pathways were significantly down-regulated and 17 pathways were significantly up-regulated, compared to gene pathways in hippocampi from male control rats. Interestingly, the hippocampi from female rats on the IF diet showed a very different functional gene pathway pattern as there were 63 significantly altered pathways, of which 3 were significantly down-regulated and 60 were significantly up-regulated, compared to gene pathways in hippocampi from control female rats.