Figure 6.

Partial suppression of cell death in Rh1 cells upon retroviral mediated ectopic expression of Pax3. After drug selection, pools of Pax3 (solid bars) and control vector (expressing β-galactosidase; shaded bars) transduced cells were incubated with 1 μM of PAX7 antisense (AS) or missense (MS) ODN and viable cells counted after 48 hr (a). (b) The same cells were treated with both PAX3 and PAX7 antisense or missense ODN at 1 μM each. Viable cells were again counted after 48 hr. For both experiments, results of three independent incubations (1–3) using at least three dishes each for cell number determination are shown expressed as ratio between MS and AS ODN incubations.