Table 3. Predicted functions of previously unannotated proteins.
| Protein | Predicted function |
|---|---|
| YFR024C-A (YSC85), YHR114W (BZZ1)*, YNL094W (APP1), YMR192W (APP2) | Actin filament organization |
| YGR268C (HUA1), YOR284W (HUA2), YPR171W (BSP1) | Actin patch assembly |
| YJR083C (ACF4) | Actin cytoskeleton organization and biogenesis |
| YDR036C (EHD3) | Protein biosynthesis in mitochondrial small ribosomal subunit |
| YKL214C (YRA2)* | mRNA processing/RNA metabolism |
| YNL207W (RIO2) | Nucleolar protein involved in 40S ribosomal biogenesis |
| YLR409C (UTP21), YKR060W (UTP30), YGR090W (UTP22), YER082C(UTP7)*, YJL069C(UTP18)*, YBR247C (ENP1) | Associated with U3 snoRNA and 20S rRNA biosynthesis |
| YMR288W (HSH155)* | snRNA binding involved in mRNA splicing |
| YHR197W (RIX1), YNL182C (IPI3), YLR106C (MDN1)* | Ribosomal large subunit assembly and maintenance |
| YGR128C (UTP8)* | Processing of 20S pre-rRNA |
| YGR215W (RSM27)*, YGL129C (RSM23)* | Structural constituent of ribosome |
| YDL213C (NOP6) | rRNA processing/transcription elongation |
| YNL306W (MRPS18)* | Mitochondrial small ribosomal subunit |
| YPR144C (UTP19), YDL148C (NOP14)*, YLR186W (EMG1), YJL109C (UTP10)*, YBL004W (UTP20) | snoRNA binding, 35S primary transcript processing |
| YGL099W (LSG1)*, YDR101C (ARX1) | 27S pre-rRNA ribosomal subunit |
| YOL077C (BRX1), YOR206W (NOC2), YNL135C (FPR1) | Biogenesis and transport of ribosome |
| YOR145C (DIM2) | 35S Primary transcript processing and rRNA modification |
| YEL015W (DCP3) | Deadenylation dependent decapping and mRNA catabolism |
| YDL002C (NHP10), YLR176C (RFX1)* | Modification of chromatin architecture/transcription |
| YDR469W (SDC1)* | Chromatin silencing and histone methylation |
| YPL070W (MUK1) | Transcription factor (or its carrier) |
| YLR427W (MAG2) | DNA N-glycosylase involved in DNA dealkylation |
| YDL076C (RXT3), YIL112W (HOS4) | Histone deacetylase complex involved in chromatin silencing |
| YNL265C (IST1) | Transcription initiation factor |
| YLR192C (HCR1)* | Translation initiation as part of elF3 complex |
| YDL074C (BRE1) | Chromosome condensation and segregation process |
| YGR156W (PTT1)*, YKL059C (MPE1)* | mRNA cleavage and polyadenylation specificity factor |
| YGR089W (NNF2) | Chromosome segregation (spindle pole) and mitosis |
| YGL161C(YIP5), YGL198W (YIP4) | Vescicle mediated transport |
| YPL246C (RBD2), YJL151C (SNA3), YGL104C (VPS73) [20], YKR030W (MSG1) | Cell wall synthesis/protein-vacuolar targeting |
| YBR098W (MMS4) | Golgi to endosome transport and vescicle organization |
| YHR105W (YPT35) | Golgi to vacuolar transport |
| YBL049W (MOH1), YCL039W (MOH2) | Both same function. Possibly linked with vacuolar transport |
| YDL246C (SOR2) | Possibly involved in fructose and mannose metabolism |
| YMR322C (SNO4) | Pyridoxine metabolism |
| YDR430C (CYM1) | Protein involved in pyurvate metabolism |
| YJL199C (MBB1), YPL004C (LSP1), YGR086C (PIL1) | Metabolic protein |
| YLR097C (HRT3) | Nuclear ubiquitine ligase |
| YKR046C (PET10) | ATP/ADP exchange |
| YEL017W (GTT3) | Protein linked with glutathione metabolism |
| YGL133W (ITC1) | Chromatin remodeling |
| YGR161C (RTS3) | Protein phosphatase 2A complex |
| YOR144C (EFD1) | DNA replication and repair |
| YML117W (NAB6) | Nuclear RNA binding |
| YLR432W (IMD3) | RNA helicase involved in mRNA splicing |
| YKL095W (YJU2), YGR278W (CWC22), YDL209C (CWC2)* | Spliceosome complex involved in mRNA splicing |
| YGR232W (NAS6)*, YGL004C (RPN14), YLR421C (RPN13)* | Proteasome complex |
*
These proteins recently were annotated in the Saccharomyces Genome Database. Except for LSG1, all other predictions provided to be correct.