Fig. 5.

A summary of the maximum level of apoptosis (percent ± SE) in p53-proficient (black) and -deficient (gray) cultures induced in proliferating cells treated with 200 μg/ml ENU (A), quiescent cells treated with 200 μg/ml ENU (subsequent to proliferation induction) (B), proliferating cells treated with a subacute cumulative dose of 1,000 μg/ml ENU (see Materials and Methods) after the final treatment (C), and proliferating cells treated with an acute dose of 1,000 μg/ml ENU (D) is illustrated.