Table 1. Clones derived from CD8+ CD28+ CLAhigh PBMC with HSV-2-specific CTL activity.
Subject | Clones screened | CTL clones* | Percent CTL clones |
---|---|---|---|
1 | 241 | 76 | 31.5 |
2 | 319 | 95 | 29.8 |
3 | 86 | 14 | 16.3 |
4 | 64 | 4 | 6.2 |
5 | 96 | 6 | 6.2 |
6 | 84 | 5 | 5.9 |
7 | 288 | 10 | 3.5 |
8 | 194 | 6 | 3.1 |
9 | 93 | 2 | 2.1 |
10 | 12 | 0 | 0 |
11† | 58 | 0 | 0 |
Clones with >25% specific release for autologous HSV-2-infected B cell targets and <10% specific release for autologous uninfected targets.
Seronegative for HSV-1 and -2, control subject.