Skip to main content
. 2003 Oct 20;100(22):12911–12916. doi: 10.1073/pnas.1735525100

Fig. 5.

Fig. 5.

Effects of IgE on mast cell numbers in vivo. Hybridoma cells secreting H1 DNP-ε-206 or H1 DNP-ε-26 IgE and hybridoma cells secreting anti-DNP IgG2b or PBS were inoculated i.p. into CAF1/J mice. Mice were killed 2 weeks later. Serum IgE and IgG2b levels were measured by ELISA, and mast cells were counted in various tissues. (A) Data for the stomach are shown for two of three separate experiments performed. (Left) n = 6–8. (Right) n = 4. Asterisks indicate statistical significance; P < 0.05 vs. values in PBS-injected mice. (B) Correlation coefficients for mast cell numbers in the stomach mucosa and serum Ig from the experiment shown on the right in A were 0.534 (P = 0.0077) for serum IgE and 0.243 (P = 0.2675) for serum IgG2b.