Table 1. T lymphocytes, gastrin, and SOM levels during H. felis infection and IL-4 treatments.
Treatment | CD3+ cells/stomach (106) | CD4+ cells/100 epithelial cells | Plasma gastrin, pmol/liter | Tissue SOM, pmol/g | |
---|---|---|---|---|---|
SOM+/+ | Fundus | Antrum | |||
PBS | 0.70±0.13 | ND | 14±2 | 1,278±38 | 2,719±108 |
H. felis | 3.56±1.17* | 192±32* | 30±2* | <2* | 1,696±101* |
IL-4 + H. felis | 0.86±0.16† | 5±3† | 12±3 | 1,127±71 | 7,096±175*† |
SOM-/- | |||||
PBS | 0.79±0.16 | ND | 63±10 | <2 | <2 |
H. felis | 3.44±0.40* | 200±37* | 94±33 | <2 | <2 |
IL-4 + H. felis | 4.59±1.42* | 199±26* | 98±38 | <2 | <2 |
ND, not determined.
P < 0.05 vs. PBS control
P < 0.05 vs. H. felis-infected mice