Fig. 2.

Linkage of the D9S1786 region of chromosome 9 to development of familial colorectal neoplasia. Chromosome 9, in cM, is depicted along the x axis. Distances of the markers were calculated relative to the first typed marker on the chromosome, D9S2169. The y axis plots pP = (-log₁₀[P value for linkage]). Red symbols depict pP values for linkage as determined by the mean test among concordantly affected sibling pairs. Blue symbols depict pP values for linkage as determined by the Haseman–Elston method employing all affected and unaffected siblings. pP values have not been corrected for multiple hypothesis testing; a pP value of 4 corresponds to a corrected logarithm of odds score of 3.