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. 1996 Nov 12;93(23):13217–13222. doi: 10.1073/pnas.93.23.13217

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Copyright © 1996, The National Academy of Sciences of the USA

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Virulence assays. Survival curves of mice (n = 10 for each C. albicans strain at each inoculation dose) infected with 1 × 10⁶ (A) and 1 × 10⁵ (B) cells of C. albicans strains SC5314 (wild type), CAI4 (ura3/ura3), CDH22 (ura3/ura3 cst20Δ/cst20Δ::URA3), and CDH10 (ura3/ura3 hst7Δ/hst7Δ::URA3). (C) Staining of mouse kidney sections with periodic acid Schiff’s stain 48 h after infection with cst20Δ/cst20Δ::URA3 mutant strain CDH22 (a) and hst7Δ/hst7Δ::URA3 mutant strain CDH10 (b). Some hyphal cells are indicated with arrows. (Bar = 0.1 mm.)

Virulence assays. Survival curves of mice (n = 10 for each C. albicans strain at each inoculation dose) infected with 1 × 10⁶ (A) and 1 × 10⁵ (B) cells of C. albicans strains SC5314 (wild type), CAI4 (ura3/ura3), CDH22 (ura3/ura3 cst20Δ/cst20Δ::URA3), and CDH10 (ura3/ura3 hst7Δ/hst7Δ::URA3). (C) Staining of mouse kidney sections with periodic acid Schiff’s stain 48 h after infection with cst20Δ/cst20Δ::URA3 mutant strain CDH22 (a) and hst7Δ/hst7Δ::URA3 mutant strain CDH10 (b). Some hyphal cells are indicated with arrows. (Bar = 0.1 mm.)