TABLE 1.
GEMSP constituents. Different families of GEMSP constituents with the respective concentration of each compound in the solution used for treating the animals. This treatment took place under identical conditions throughout the experiments, using the same lot number. Lyophilised GEMSP was reconstituted with purified water before subcutaneous injection. AA: amino acids; M: molarity; PL: Poly-L.Lysine
| Families of Compounds | Different Constituents of GEMSP Linked to PL | Final Concentration of GEMSP (M) |
|---|---|---|
| Fatty Acids | Azelaic Acid - PL - Oleic Acid | 1.00E-03 |
| Azelaic Acid - PL - Palmitoleic Acid | 1.00E-03 | |
| T-T-Farnesyl-L.Cysteine - PL - Oleic Acid | 1.00E-03 | |
| Oleic Acid - PL - Palmitic Acid | 1.00E-03 | |
| Oleic Acid - PL - Myristic Acid | 1.00E-03 | |
| Oleic Acid - PL - Linoleic Acid | 1.00E-03 | |
| Oleic Acid - PL - Thioctic Acid | 2.00E-04 | |
| Cholesterol -PL - Oleic Acid | 1.00E-03 | |
| Linoleic Acid - PL | 1.00E-03 | |
| Oleic Acid - PL - Palmitoleic Acid | 1.00E-03 | |
| T-T-Farnesyl-L.Cysteine - PL - Palmitic Acid | 2.00E-04 | |
| Antioxidants | α-Tocopherol-succinate - PL | 2.00E-04 |
| Ascorbic Acid - PL | 2.00E-04 | |
| AA and Derivatives | L.Methionine - Reduced Glutaraldehyde - PL | 2.00E-04 |
| L.Cysteine - Reduced Glutaraldehyde - PL | 2.00E-04 | |
| Taurine - Reduced Glutaraldehyde - PL | 2.00E-04 | |
| Histamine - Glutaric Anhydride - PL | 4.00E-04 | |
| L.Histidine - Glutaric Anhydride - PL | 4.00E-04 | |
| 5-Methoxytryptamine - Glutaric Anhydride - PL | 4.00E-04 |