Table 5.
Hazard Ratios for all-cause mortality by quartiles of NT-proBNP and c-TNT separately and considered together
| Biomarker | All-cause mortality | Adjusted All-cause mortality | |||||
|---|---|---|---|---|---|---|---|
| NT-proBNP | Range (pg/mL) | HR | 95 % CI | p | HR | 95 % CI | p |
| Quartile 1 | 215-1150.5 | 1 | 1 | ||||
| Quartile 2 | 1150.5-3276.5 | 2.09 | 0.63 - 6.95 | 0.2 | 2.01 | 0.61-6.69 | 0.03 |
| Quartile 3 | 3276.5-7880.5 | 5.86 | 1.97-17.4 | 0.001 | 5.21 | 1.73-15.67 | <0.01 |
| Quartile 4 | 7880.5- ≥ 35000 | 4.79 | 1.61-14.23 | <0.01 | 3.72 | 1.18-11.72 | 0.03 |
| LRT | χ2 − 3.42, p=0.33 | ||||||
| cTnT | Range (ng/mL) | ||||||
| Quartile 1 | ≤ 0.01 - 0.022 | 1 | 1 | ||||
| Quartile 2 | 0.022 - 0.056 | 1.95 | 0.67 - 5.71 | 0.2 | 1.95 | 0.66-5.73 | 0.22 |
| Quartile 3 | 0.056 - 0.106 | 3.28 | 1.20 - 8.98 | 0.02 | 2.28 | 0.81-6.46 | 0.12 |
| Quartile 4 | 0.106 - 0.569 | 3.13 | 1.20 - 9.12 | 0.02 | 2.4 | 0.84-6.91 | 0.10 |
| LRT | χ2 − 12.4, p<0.01 | ||||||
Adjusted all-cause mortality for NT-proBNP is adjusted for cTnT. Adjusted all-cause mortality for cTnT is adjusted for NT-proBNP. HR= Hazard Ratio; CI = confidence interval. , LRT=Likelihood ratio test comparing the model incorporating the adjustment to the unadjusted model.