Table 6.
Hazard Ratios for all-cause mortality by echocardiographic and biomarker parameters
| Model | Biomarker | Range (g/m2.7) |
HR | 95 % CI | p | LR χ2 |
|---|---|---|---|---|---|---|
| 1 | LVMI | 1.4 | ||||
| Quartile 1 | <48.8 | 1 | ||||
| Quartile 2 | 48.8-58.2 | 0.96 | 0.41 - 2.26 | 0.93 | ||
| Quartile 3 | 58.2-70.2 | 1.2 | 0.54 - 2.68 | 0.65 | ||
| Quartile 4 | >70.2 | 0.72 | 0.30 - 1.74 | 0.47 | ||
| 2 | mWFS | Range (%) | 11.1 | |||
| Quartile 1 | >16.1 | 1 | ||||
| Quartile 2 | 16.1-14.7 | 0.86 | 0.32-2.30 | 0.77 | ||
| Quartile 3 | 12.4-14.7 | 1.05 | 0.39-2.79 | 0.93 | ||
| Quartile 4 | <12.4 | 2.78 | 1.22-6.36 | 0.015 | ||
| 3 | log cTnT | 1.61 | 1.19-2.17 | 0.002 | 10 | |
| 4 | log NT-proBNP | 1.63 | 1.27-2.09 | <0.001 | 15.3 | |
| 5 | LVMI + log cTNT | 11.8 | ||||
| log cTnT | 1.65 | 1.21-2.25 | 0.002 | |||
| 6 | mWFS + log cTNT | 20.9 | ||||
| log cTnT | 1.63 | 1.19-2.22 | 0.002 | |||
| 7 | LVMI + mWFS + log cTnT | 25.6 | ||||
| log cTnT | 1.71 | 1.25-2.34 | 0.001 | |||
| 8 | LVMI + log NT-proBNP | |||||
| log NT-proBNP | 1.71 | 1.30-2.24 | <0.001 | 17.4 | ||
| 9 | mWFS + log NT proBNP | 21.7 | ||||
| log NT-proBNP | 1.57 | 1.18-2.07 | 0.002 | |||
| 10 | LVMI + mWFS + log NT-proBNP | 26.5 | ||||
| log NT-proBNP | 1.65 | 1.24-2.20 | 0.001 |
LVMI= left-ventricular mass index, mWFS= midwall fractional shortening, cTNT = cardiac troponin-t, NT-proBNP = n-terminal pro B-type natriuretic peptide, HR=Hazard ratio, CI=Confidence interval