Table 3. Hydrophobicity index and composition of bile in middle and late lactating rats.

	Control	PP day 10	PP day 14	PP day 19–23
Hydrophobicity index	−0.48±0.01	−0.38±0.04*	−0.38±0.01*	−0.31±0.02‡
Bile composition (mole%)
Cholic acids	20.1±1.4	26.4±3.3	31.2±1.3‡	31.7±1.3‡
Chenodeoxycholic acids	3.6±0.3	8.4±0.7	6.1±1.2	6.9±1.3
Muricholic acids	74.9±0.6	64.6±3.4†	62.0±0.7‡	59.9±2.2‡

All data are expressed as means ± SD. Bile acids were extracted from control female rats and PP rats at days 10, 14, and 19–23. Bile acids are expressed as a percentage of the total recovered (mole %). Cholyl conjugates: tauroursodeoxycholic acid, taurocholic acid, glycocholic acid, and taurodeoxycholic acid. Chenodeoxycholic acids: taurochenodeoxycholic acid and glychochenodeoxycholic acid. Muricholic acids: tauro-α and β-muricholic acids and glyco-β muricholic acid.

^*P < 0.05.

^†P < 0.01.

^‡P < 0.001 vs. control rats as determined by one-way ANOVA, followed by Bonferroni's multiple comparisons test.