Table 1.
Age | wt
|
AChRɛ−/−
|
||
---|---|---|---|---|
A, nA | τ, ms | A, nA | τ, ms | |
P4–P5 | 3.3 ± 0.5 | 4.2 ± 0.3 | 3.4 ± 0.4 | 5.1 ± 0.6 |
P30–P32 | 3.3 ± 0.5 | 1.3 ± 0.1 | 2.1 ± 0.3 | 4.7 ± 0.6 |
P65–P75 | 3.1 ± 0.4 | 1.1 ± 0.1 | 0.9 ± 0.2 | 4.4 ± 0.7 |
The mean peak amplitude (A) and decay time constants (τ) of mEPCs recorded from hemidiaphragms of wild-type (wt) or AChRɛ−/− mice were determined for each end plate from between 45 and 210 mEPCs measured individually. All mEPCs had fast rise times (<0.5 ms for 20–80% peak amplitude rise time). Means ± 1 SD are given, and the number of end plates was between 7 and 9 for each mean. All experiments at −70 mV, temperature 20–21°C.