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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Dev Biol. 2008 Jan 22;315(1):114–124. doi: 10.1016/j.ydbio.2007.12.014

Figure 2.

Figure 2

Medial and lateral streams of aggrecan-rich cells in E8 hindbrain cross-sections follow a pattern seen with astroglial markers and not markers of postmitotic neurons or oligodendrocytes. A, Aggrecan gene expression, showing labeled cells (arrows) that appear to be migrating from the VZ. B–D, Similarly positioned streams (but ones differing greatly in their density of labeling) are identified with the astrocyte markers GLAST (B), GLUL (C) and BLBP (D). E, F, Labeling of VZ and medial and lateral streams are not seen with the neuronal marker class III beta-tubulin/TUBB3 (E) or the oligodendrocyte marker PLP1 (F). G, H, Gene expression distributions of the intermediate filament nestin/NES (F) and the aggrecan family member brevican/BCAN (H) are more extensive than those of aggrecan but include key features such as strong VZ labeling. No hybridization signal for the intermediate filament gene GFAP (glial fibrillary acidic protein) was detected at this stage (not shown).